This correspondence is principally concerned with business between Pershouse and his brother James in England, with comments on conditions and events in the United States, including anti-British feeling, Thomas Paine's return to America, Jefferson's administration, and immigration. The papers include Pershouse's journal (1800-1838), which includes accounts of travels in England, France, and the United States, letterbooks (1836-1862) of Henry Pershouse, nephew of John, chiefly on business matters, and two volumes of Pershouse genealogical data, compiled by B.M. Pershouse Bayley (1899).

The correspondence is principally to Zaccheus Collins (1810-1840), with bills, receipts, and notes on Rafinesque vs. Parker; letters from Collins, L.A. Tarascon, Lewis C. Beck, John Torrey, and Charles W. Short (1817-1835); and miscellaneous correspondence and documents relating to Rafinesque vs. Parker, with an account of the Felician Society of Feliciana County, Illinois (1820). The writings are chiefly on botanical topics, and include notes and essays on Indians, Blacks, grapes and wine-making, banking, and speculation. Rafinesque's growing interest in Indian antiquities, linguistics, and history is apparent in letters after 1820. There is an account of Rafinesque's scientific travels in North America and southern Europe (1800-1832), and a bibliography. The botanical notes include descriptions of specimens collected by Lewis and Clark, Patrick Gass, and Henry Muhlenberg.

These letters and papers include ten small volumes of letterbooks (1752-1781), and ca. 100 pieces of correspondence with Joseph Shippen (1750-1778). Topics discussed are business in Philadelphia and Lancaster, provincial politics, army supply in the French and Indian War, land purchases and speculation, housebuilding, and family affairs.

In addition to family and business correspondence, the Charles Nicoll Bancker Family Papers contains various documents, such as a furniture inventory volume (30pp.); a Daybook, 1795-1800 (120pp.); and a very interesting journal (unidentified, but by one of the Banckers, and filed under "Description of a trip..."), from New York to Albany and back, between July 20-Aug. 15, 1793 (1 vol., 31 pp.). It contains detailed observations of the Hudson River and the towns along the way. Bancker was involved in business and trade prior to 1826, and in insurance after that date, so there is material relating to those topics in this collection. He owned a substantial library of the period, which was used by Charles Wilkes's Expedition after 1837 (see Reynell Coates to Bancker). This library, along with Bancker's notable scientific instrument collection, was sold after his death and there are published auction catalogues in the collection. There is much family correspondence from: Anne E. Bancker, Charles Gerard Bancker, Evert Bancker, Sarah U. Bancker, Violetta Bancker Talbot, Elizabeth Bancker Teackle, and John Teackle.

A physician, natural historian, and professor at the University of Pennsylvania, Benjamin Smith Barton (1766-1815) was one of the central figures in Philadelphia's early national scientific establishment. Having received his medical training in European universities, Barton was appointed Professor at the University of Pennsylvania in 1789, lecturing on botany, materia medica, natural history. A prolific author, he established his reputation as one of the nation's preeminent botanists through his botanical text book The Elements of Botany (1803), but his contribtions to zoology, ethnology, and medicine were equally noteworthy. Barton's monograph on the "fascinating faculty" of the rattlesnake and his efforts in historical linguistics (New Views of the Origin of the Tribes and Nations of America, 1798) were widely read, and his Philadelphia Medical and Physical Journal (1804-1809) was one of the nation's first medical journals and an important outlet for natural historical research. The Barton Papers offer a comprehensive view of the professional work of Benjamin Smith Barton from the time of his return to the United States in 1789 until his death. The collection is divided into five series: Correspondence, Subject Files, Bound Volumes, Graphic Materials, and Printing Plates. The collection includes a particularly valuable series of botanical, medical, and natural historical drawings collected by Barton for research, reference, and publication. Among the many artists represented are William Bartram, Frederick Pursh, Pierre Turpin, and Benjamin Henry Latrobe.

A collection of business and personal papers of three generations of the prominent Philadelphia Jewish family from 1750-1974. Business records include trade and land transactions (some in Yiddish) of the Gratz brothers, Barnard and Michael (1750-1804) with the business continued by Michael's sons: Simon, Hyman, Joseph, Jacob, and Benjamin (1791-1861). Personal correspondence are primarily letters to Rebecca Gratz from her sisters Rachel and Sarah (1795-1867) with later correspondence to Rachel's children: Horace and Sara Moses (1832-1879). Contains a small group of French letters related to Napoleon III, collected by family member Miriam Fox, and some heirloom artifacts.